赵伟利
药物化学, 研究员, 博士生导师

姓      名

 赵伟利

性      别

 男

职      称

 研究员

学      历

 博士

电      话

 021-51980111

传      真

 021-51980111

电子邮件

zhaoweili@fudan.edu.cn

个人主页


通讯地址

 张衡路826号实验南楼421

教育经历1998.10-2002.10 瑞士联邦苏黎世理工学院,博士后
1998.07-1998.10 美国加州理工学院,博士后
1997.07-1998.07 美国加州大学尔湾分校,访问学者
1994.07-1997.07 中国科学院感光化学研究所,博士
1987.07-1990-07 中国科学院感光化学研究所,硕士
1983.07-1987.07 武汉大学化学系,学士

 

工作经历 2009.04-   澳门新葡亰www496cn, 研究员、博导
2005.11-2009.03 罗氏研发(中国)有限公司,药物研发副主任、主任
2002.10-2005.11 瑞士联邦苏黎世理工学院“Wissenschaftlicher Mitarbeiter”
1990.07-1994.07 河南大学物理系,助教,讲师

 
研究方向
1.抗肿瘤小分子靶向药物研究
2.有机合成方法
3.荧光探针及传感器

 

代表性论著

1. Response to Comment on “Water-Soluble Fluorescent Probe with Dual Mitochondria/Lysosome Targetability Superoxide Detection in Live Cells and in Zebrafish Embryos”. Xiuhong Lu, Guangyu Lin, Xiaochun Dong*, Weili Zhao*, Zhongjian Chen*, ACS Sens.,2019, 4, 3084-3087.

2. Pyridinium substituted BODIPY as NIR fluorescent probe for simultaneous sensing of hydrogen sulphide/glutathione and cysteine/homocysteine. Jian Zhang, Xin Ji, Junliang Zhou, Zhongjian Chen*, Xiaochun Dong*, Weili Zhao*,Sens. Actuators B,2018, 257, 1076–1082.

3. Water-Soluble Fluorescent Probe with Dual Mitochondria/Lysosome Targetability for Selective Superoxide Detection in Live Cells and in Zebrafish Embryos. Xiuhong Lu, Zhongjian Chen*, Xiaochun Dong*, Weili Zhao*,ACS Sens.,2018, 3, 59?64.

4. Overcoming the resistance mechanisms of Smoothened inhibitors. Xiaochun Dong, Chenglin Wang, Zhongjian Chen*, Weili Zhao*,Drug Discov. Today,2018, 23, 704–710.

5. A mitochondria-targeted turn-on ?uorescent probe for the detection of glutathione in living cells. Jian Zhang, Xiaolong Bao, Junliang Zhou, Fangfang Peng, Hang Ren, Xiaochun Dong*, Weili Zhao*,Biosens. Bioelectron.,2016, 85, 164–170.

6. A multi-functional probe to discriminate Lys, Arg, His, Cys, Hcy and GSH from common amino acids.Xiuhong Lu, Wen Wang, Qian Dong, Xiaolong Bao, Xianfeng Lin, Weixing Zhang, Xiaochun Dong*, Weili Zhao*,Chem. Commun.2015, 51, 1498-1501.

7. A Facile Copper-Catalyzed One-Pot Domino Synthesis of 5,12-Dihydroindolo[2,1-b]quinazolines

Min Jiang, Xiaochun Dong, Weili Zhao*,Org. Lett. 2012, 14, 1420-1423.

8. Microwave-Assisted Solventless Reaction of Iridium-Catalyzed Alkylation of Amines with Alcohols in the Absence of Base.Weixing Zhang, Xiaochun Dong*, Weili Zhao*,Org. Lett.2011, 13 (19), 5386-5389.

9. One-Pot Synthesis of Novel Photochromic Oxazine Compounds. Weili Zhao*, E. M. Carreira*, Org. Lett. 2011, 13 (19), 5084-5087.


 

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